Friday, 14 December, 2018

Breast Cancer Study: Chemo Not Required

In a rare triumph for tough-to-beat pancreatic cancer patients who had surgery lived substantially longer on a four-drug combo than on a standard cancer drug according to research released on Monday Many Breast Cancer Patients May Not Need Chemotherapy
Johnnie Parks | 08 June, 2018, 10:46

Dr Epstein, a clinical oncologist at Memorial Sloan Kettering Cancer Centre in NY, said the two studies show "the anti-inflammatory benefits of a relatively cheap, well-tolerated supplement".

Dr Alistair Ring, a consultant at the Royal Marsden Hospital in London, thinks that 3,000 women a year in the United Kingdom will not need chemotherapy anymore because of this trial.

However an estimated 25% of patients stop within two years because they can not endure the side effects, lead author Dr Sherry Shen, of the New York Presbyterian Hospital, said.

The study was supported in part by the Breast Cancer Research Foundation, Komen Foundation, and the Breast Cancer Research Stamp. Some study leaders consult for breast cancer drugmakers or for the company that makes the gene test. When chemo is used now, it's sometimes for shorter periods or lower doses than it once was.

In a new analysis, researchers examined 9,717 women between the ages of 18 and 75 with early-stage breast cancer that had not spread to lymph nodes. Doctors know that most don't need it, but evidence is thin on who can forgo it.

In the USA, those who score low on the test - 0-10 - are already told to skip chemotherapy after their tumours are removed and they receive hormone therapy.

"70% of women with the most common form of early stage breast cancer could be treated safely with just surgery and hormone therapy."
At nine years, the two treatment groups had similar rates of invasive disease-free survival (83.3% in the endocrine therapy group and 84.3% in the chemoendocrine therapy group). In contrast, for patients with a low recurrence score (0-10), the benefits of chemotherapy are unlikely to outweigh the risks and toxicity.

- Local breast cancer doctors are excited about the results of a trial involving 10,000 women.

Liverpool closing in on Nabil Fekir deal with Lyon
The Lyon captain is the Reds' primary target as they seek to add creativity to their attacking midfield options. The France worldwide is on the verge of a move to Anfield ahead of the World Cup .


It's all but over for the Cinderella Golden Knights — SNAPSHOTS
Vegas has won four straight games after consecutive losses, and they are 8-3 total in their inaugural season in this situation. Then he popped the puck up and over goalie Marc-Andre Fleury. "What happened was obviously pretty negative", Smith-Pelly said.


Paul Ryan Contradicts Donald Trump on Spygate and the Federal Bureau of Investigation
Appearing on the Lou Dobbs show Wednesday, Gaetz offered a scathing critique of what he saw as Ryan's betrayal of the president. Hours after Ryan's comments, Burr told The Associated Press that he, too, agreed with Gowdy.


The researchers said ongoing clinical trials are obtaining additional information on the clinical usefulness of the 21-gene assay in women with hormone receptor-positive breast cancer and positive axillary nodes, and evaluating the clinical usefulness of the 50-gene assay in this context. "And this is the promise of personalized medicine, and it's arrived", Agus said. The money was used to pay for the gene test, which costs more than $4,000 per person.

Testing solved a big problem of figuring out who needs chemo, said Dr. Harold Burstein of the Dana-Farber Cancer Institute in Boston.

The patients affected by these new study results are those with estrogen-sensitive breast cancers who also test negative for the HER2 gene.

Dr. Jennifer Litton at MD Anderson Cancer Center in Houston, agreed, but said, "Risk to one person is not the same thing as risk to another. Towards the end, my eyes would water", she said. Other folks need chemo for the tiniest possibility of advantage.

"I was somewhat relieved". She said, "I was in the grey area". The treatments "weren't pleasant", she concedes.

"I lost my hair".

"If physicians had recommended she bypass chemo Depending on the chemical test,"that I Would have confessed that", she explained. research". "I'm a firm believer in medical research".

Recommended

  • Hitman 2 Arriving November 13, 2018

    Hitman 2 Arriving November 13, 2018

    From sun-drenched streets to dark and risky rainforests, nowhere is safe from the world's most creative assassin, Agent 47 . Io Interactive and Warner Bros . will release Hitman 2 on the PlayStation 4, Xbox One and PC on November 13, 2018.
    Kevin Durant Held Back From Heckling Cavs Fan

    Kevin Durant Held Back From Heckling Cavs Fan

    He became the sixth player in Finals history to top 50 points, and the only one to lose in the process. But since being traded to Cleveland in mid-season, he's been hard to find on the court.
    Comedian Michael McIntyre 'fine' after being robbed by moped thugs

    Comedian Michael McIntyre 'fine' after being robbed by moped thugs

    Popular comedian Michael McIntrye was robbed whilst waiting outside his son's school on Monday afternoon, in a terrifying attack. Anyone with information is asked to call police on 101 quoting CAD4018/04JUN or call Crimestoppers anonymously on 0800 555 111".
  • Warriors-Cavaliers Game 3

    Warriors-Cavaliers Game 3

    For years, the Patriots have exploited slip-ups by their opponents while (mostly) playing mistake-free football themselves. He said he tried to "fast track" Kryie Irving's mind when James returned to Cleveland four years ago.
    Stanley Cup: Three takeaways from Capitals' first title

    Stanley Cup: Three takeaways from Capitals' first title

    But Vegas played an urgent game that was both fast-paced and physical, out-hitting Washington 18-10 in the first. It's not a sure bet, but if you believe Vegas will come out strong in this one it's worth investing a unit.
    BlackBerry KEY2 unveiled, touts physical keyboard and touch display

    BlackBerry KEY2 unveiled, touts physical keyboard and touch display

    BlackBerry says the KEY2 will arrive later this month for $649, making it $100 more expensive than last year's KeyOne at launch. The new BlackBerry KEY2 will be made available as pre-order in select markets throughout the world starting from this month.
  • Burnley goalkeeper Nick Pope set to make England debut against Costa Rica

    Burnley goalkeeper Nick Pope set to make England debut against Costa Rica

    A strong first 45 minutes but a less convincing second resulted in a 2-1 win for England against Nigeria on Saturday night. Gareth Southgate will hand 19-year-old Trent Alexander-Arnold his England debut and Jack Butland will also start in goal .
    Rocks on Mars still harbour organic molecules after billions of years

    Rocks on Mars still harbour organic molecules after billions of years

    Mars2020 will shed light on the organic molecules-and prepare a sample that some future mission could bring back to Earth . Still, this discovery is very encouraging in the context of what we know about Mars in the distant past.
    Gov't: Medicare will become insolvent in 2026, Social Security in 2034

    Gov't: Medicare will become insolvent in 2026, Social Security in 2034

    The trustees include Treasury Secretary Steven Mnuchin and Health and Human Services Secretary Alex Azar. It will decline further to about 2.2 by 2035, when most baby boomers will have retired, officials said.
  • UItimate U-turn, horrific deja vu in Socceroos final WC squad

    UItimate U-turn, horrific deja vu in Socceroos final WC squad

    After the match, Van Marwijk said he was "satisfied" with his players' performance. I got him because of the injury to Juric. "I think I need him".
    Golden State Warriors take 3-0 lead in NBA Finals

    Golden State Warriors take 3-0 lead in NBA Finals

    To end the first half, he made a 34-foot 3-pointer to trim the deficit to six after the Cavaliers held a 13-point advantage. Consider the how-to-beat-the Warriors checklist, and how many items on that list could reasonably be marked off in Game 3.
    Zverev reaches French Open quarters

    Zverev reaches French Open quarters

    The unseeded Cecchinato, who broke down in tears after the match, next faces Thiem for a place in Sunday's final. Unfortunately, it took me time to get well, and struggled with a little injury, as well, at the beginning.

Amazon Officially Announces The Fire TV Cube Amazon Officially Announces The Fire TV Cube With compatible A/V receivers, you'll even be able to ask Alexa to switch your inputs and change the volume, which is pretty cool. According to today's official release, the Amazon Fire TV Cube will go on sale in the USA on 21 June.

Inside Kate Spade's Final Days Before Her Shocking Death Inside Kate Spade's Final Days Before Her Shocking Death Andy Spade said that the couple had been living apart but in the same neighborhood, caring for their 13-year-old daughter Bea. Spade and her husband sold their remaining stake in the company in 2006 to Neiman Marcus for almost $60 million.

As field for California governor narrows to two, Democrats plot strategy As field for California governor narrows to two, Democrats plot strategy California's unusual primary system allows the top two primary candidates to advance to the general election, regardless of party. Ed Royce and Darrell Issa , and the district where Republican Dana Rohrabacher was facing challenges from the left and the right.

Scott Pruitt Made Staff Drive Him Around To Find His Favorite Lotion Scott Pruitt Made Staff Drive Him Around To Find His Favorite Lotion Early this year, two of Pruitt's top aides received large raises: 52 percent in one case and 33 percent in the other. The Post notes that "federal ethics laws bar public officials from using their position or staff for private gain".

Kaala Leaked Online On The Very First Day Of Its Release? Kaala Leaked Online On The Very First Day Of Its Release? They are shutting by themselves and are not screening Kaala . "Cauvery water is more important than a Rajinikanth film for us". In Bengaluru , single-screen theaters known to release Tamil movies are not screening the movie amidst protests.

Late night shows slam Trump over canceled Eagles White House visit Late night shows slam Trump over canceled Eagles White House visit At the end of the day I don't think it's about a statement. "It hasn't come up here, but I think I already have my mind made up". Philadelphia Eagles head coach Doug Pederson spoke bluntly: "It's over.

Val Kilmer Joins Tom Cruise in ‘Top Gun: Maverick’ Val Kilmer Joins Tom Cruise in ‘Top Gun: Maverick’ Top Gun 2 , which likely will have the title of Top Gun: Maverick , is officially happening over at Paramount. Last week, Cruise actually shared the first picture from the movie and it made a lot of '80s kids excited.

Romanian star Simona Halep reaches Roland Garros final for the third time I think I have to put a lot of things in perspective for the last, what, four, five weeks since the clay season. As great a mover and defender as Halep is, she could be left powerless if Muguruza is at her imposing best.

AMD announces Threadripper 2 processors - AMD AMD announces Threadripper 2 processors - AMD On the other side, AMD rendered an image, Quote: "on an air cooling system" while using their Threadripper 2. AMD showed off the 7nm GPU in action, paired with 32GB of HBM2 memory in a Cinema4D rendering demonstration.

Your Private Facebook Posts May Have Been Public For Days Your Private Facebook Posts May Have Been Public For Days In the meantime, it has reverted the audience for any affected posts to whatever setting the user had selected previously. The software flaw was apparently live for 10 days last month and the company didn't give users any kind of warning.

Trump says he doesn't need to 'prepare very much' for Kim summit The anticipated summit almost was derailed in May when US National Security Adviser John Bolton compared the North Korea situation to Libya.

White House Analysis Finds Tariffs Will Hurt Growth, as Officials Insist Otherwise White House Analysis Finds Tariffs Will Hurt Growth, as Officials Insist Otherwise But a negative WTO outcome for the US would open the path to punitive tariffs from USA trade partners. The member countries are: Canada, France, Italy, Japan, Germany, the United States and the Britain.

State Department sends personnel for screenings in U.S. after China acoustic incident State Department sends personnel for screenings in U.S.  after China acoustic incident Vehicles pass by high-rise apartment buildings in The Canton Place where U.S. government workers experienced unexplained illnesses.

The rattlesnake was decapitated. Its head still bit a man The rattlesnake was decapitated. Its head still bit a man Between 6,000 and 8,000 people are bitten by snakes in the United States each year, with 10-12 of those people dying. A Texas man is recovering after he claims the head of a rattlesnake bit him - moments after he had just cut it off.

Israeli troops shoot dead Palestinian stone-thrower Israeli troops shoot dead Palestinian stone-thrower Since 2015, Palestinians have killed over 50 Israelis, two visiting Americans and a British tourist in stabbings, shootings and car-ramming attacks.